本產品以即時定量甲基化特異性基因檢測技術,偵測子宮頸細胞檢體中特定基因的甲基化,可作為醫師用於是否罹患子宮頸癌或癌前病變的輔助評估工具。
- 20歲(含)以上的女性
- 較早有性經驗的女性
- 曾發生細胞學異常或感染高危險型HPV者
- 有癌症家族病史的女性
- 子宮異常出血者
- 常出現生殖道感染或慢性發炎者
- 免疫系統缺陷族群
- 抽菸的女性
- 其他子宮頸癌的高風險族群
檢測優勢
檢測流程
檢測優勢
檢測流程
臨床實證
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Chang CL, Ho SC, Su YF, et al. DNA methylation marker for the triage of hrHPV positive women in cervical cancer screening: Real-world evidence in Taiwan.Gynecol Oncol. 2021 May; 161(2): 429-435.
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Tain Y, Yuan Wu NY, Liou YL, et al. Utility of gene methylation analysis, cytological examination, and HPV-16/18 genotyping in triage of high-risk human papilloma virus-positive woman. Oncotarget. 2017 Jul 22;8(37): 62274-62285. Oncotarget. 2017 Jul 22;8(37): 62274-62285.
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Lion YL, Zhang TL,Yan T, et al.Combined clinical and genetic testing algorithm for cervical cancer diagnosis. Clin Epigenetics. 2016 Jun 10;8:66.
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Liou YL, Zhang Y, Liu Y, et al. Comparison of HPV genotyping and methylated ZNF582 as triage for women with equivocal liquid-based cytology results. Clin Epigenetics. 2015 Apr 28;7(1):50.
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Kan YY, Liou YL, Wang HJ, et al. PAX1 Methylation as a Potential Biomarker for Cervical Cancer Screening. Int J Gynecol Cancer.2014 Jun;24(5):928-34.
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